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丹桂飘香，秋风送爽，在这个收获的季节，威廉希尔足球官网和中国生物物理学会纳米生物学分会主办，WILEY出版集团发行的国际综合性期刊《Exploration》第一期正式上线！

主编寄语

感谢《Exploration》第一期论文的作者、审稿专家以及编辑出版团队的辛勤努力，首卷首期共发表文章8篇。其中，1篇Editorial，1篇Perspective，4篇Research Article以及2篇Review。论文内容涵盖纳米、植物、化学、物理、药学、能源等多个学科，作者来自中国、美国、法国、日本、德国等10个国家。充分体现了期刊立足学科交叉的综合性国际期刊的定位，也展示了期刊 “精品至上”的办刊理念。

探索引领创新，探索赢得未来！《Exploration》将立足国家创新驱动发展战略，聚焦打破学科界限的交叉学科等综合性研究成果及前沿进展，竭力为广大科研工作者提供一个高端的国际学术交流和传播平台。在探索中寻找科学的亮光、追寻真理的步伐！

我们的编辑出版团队会“守正笃实，久久为功”，坚持以创新水平和科学价值为选稿用稿的唯一标准，不断提高期刊的国际学术影响力，争取获得《Exploration》的首个影响因子在15左右，为推动国家科技文献出版事业发展尽心竭力，贡献一份力量！

我们希望，《Exploration》这棵得到了广大同仁支持和关照的科技综合期刊小苗，可以成长为一株参天大树，并傲然屹立于世界科技期刊之林。

Explore unknown scientific knowledge and innovative technology.

首期共刊发8篇文章：

1，主编梁兴杰研究员和执行主编师冰洋教授共同撰写的创刊词，对《Exploration》创刊意义、宗旨和愿景进行介绍，“Exploration: Explore a better future with advanced science and technology”；

2，威廉希尔足球官网宋纯鹏教授、澳大利亚科学院院士John Patrick教授与Tina Offler教授课题组合作撰写的前瞻评述, “From mouse to mouse-ear cress: Nanomaterials as vehicles in plant biotechnology”；

3，期刊主编中国科学院国家纳米科学中心梁兴杰研究员与法国马赛纳米科学跨学科研究中心彭玲研究员课题组共同撰写的研究论文，"Dendrimeric nanosystem consistently circumvents heterogeneous drug response and resistance in pancreatic cancer”；

4，期刊副主编北京理工大学黄渊余教授课题组撰写的研究论文，"Membrane-destabilizing ionizable lipid empowered imaging-guided siRNA delivery and cancer treatment”；

5，期刊副主编上海大学陈雨教授课题组撰写的研究论文，"Mitochondria-specific nanocatalysts for chemotherapy-augmented sequential chemoreactive tumor therapy”；

6，期刊副主编南开大学薛雪教授与沈阳药科大学吴春福教授课题组撰写的研究论文，“Receptor-targeting nanomaterials alleviate binge drinking-induced neurodegeneration as artificial neurotrophins”；

7，期刊副主编中国科学院生物物理研究所范克龙研究员与中科院院士阎锡蕴教授课题组共同撰写的综述论文，“Nanozyme for tumor therapy: Surface modification matters”；

8，中国科学院北京纳米能源与系统研究所王中林院士，威廉希尔足球官网郑海务教授与武汉大学国世上教授课题组共同撰写的综述论文，“Self-powered technology based on nanogenerators for biomedical applications”。

首期文章信息概览

01 | Inaugural Editorial

Exploration: Explore a better future with advanced science and technology

Yang Liu, Bingyang Shi, Xing-Jie Liang

DOI: 10.1002/EXP.20210100

02 | Perspective

From mouse to mouse‐ear cress: Nanomaterials as vehicles in plant biotechnology

Xue Xia, Bingyang Shi*, Lei Wang, Yang Liu, Yan Zou, Yun Zhou, Yu Chen, Meng Zheng, Yingfang Zhu, Jingjing Duan, Siyi Guo, Ho Won Jang, Yuchen Miao, Kelong Fan, Feng Bai, Wei Tao, Yong Zhao, Qingyu Yan, Gang Cheng, Huiyu Liu, Yan Jiao, Shanhu Liu, Yuanyu Huang, Daishun Ling, Wenyi Kang, Xue Xue, Daxiang Cui, Yongwei Huang, Zongqiang Cui, Xun Sun, Zhiyong Qian, Zhen Gu, Gang Han, Zhimou Yang, David Tai Leong, Aiguo Wu, Gang Liu, Xiaogang Qu, Youqing Shen, Qiangbin Wang, Gregory V. Lowry, Ertao Wang, Xing-Jie Liang, Jorge Gardea-Torresdey, Guoping Chen, Wolfgang J. Parak, Paul S. Weiss, Lixin Zhang, Martina M. Stenzel, Chunhai Fan, Ashley I. Bush, Gaiping Zhang, Christopher P. L. Grof, Xuelu Wang, David W. Galbraith, Ben Zhong Tang, Christina E. Offler*, John W. Patrick*, Chun-Peng Song*

DOI: 10.1002/EXP.20210002

03 | Research Article

Dendrimeric nanosystem consistently circumvents heterogeneous drug response and resistance in pancreatic cancer

Juan Liu, Chao Chen, Tuo Wei, Odile Gayet, Céline Loncle, Laurence Borge, Nelson Dusetti, Xiaowei Ma, Domenico Marson, Erik Laurini, Sabrina Pricl, Zhongwei Gu, Juan Iovanna, Ling Peng*, Xing-Jie Liang*

DOI: 10.1002/EXP.20210003

04 | Research Article

Membrane-destabilizing ionizable lipid empowered imaging-guided siRNA delivery and cancer treatment

Shuai Guo, Kun Li, Bo Hu, Chunhui Li, Mengjie Zhang, Abid Hussain, Xiaoxia Wang, Qiang Cheng, Feng Yang, Kun Ge, Jinchao Zhang, Jin Chang, Xing-Jie Liang, Yuhua Weng, Yuanyu Huang

DOI: 10.1002/EXP.20210008

05 | Research Article

Mitochondria-specific nanocatalysts for chemotherapy-augmented sequential chemoreactive tumor therapy

Hui Huang, Caihong Dong,* Meiqi Chang, Li Ding, Liang Chen, Wei Feng,* and Yu Chen*

DOI: 10.1002/EXP.20210149

06 | Research Article

Receptor-targeting nanomaterials alleviate binge drinking-induced neurodegeneration as artificial neurotrophins

Jingyu Yang†, Chunxiao Wang†, Bingyang Shi, Lirong Wang, Lihuan Bai, Yuequan Shen, Liwen Huang, Xiaohang Che, Zhen Zhang, Ping Liu, Yanan Zhao, Xiaomei Hu, Xing-Jie Liang, Chunfu Wu*, Xue Xue*

DOI: 10.1002/EXP.20210004

07 | Review

Nanozyme for tumor therapy: Surface modification matters

Guoheng Tang, Jiuyang He, Juewen Liu, Xiyun Yan*, Kelong Fan*

DOI: 10.1002/EXP.20210005

08 | Review

Self-powered technology based on nanogenerators for biomedical applications

Yuanzheng Zhang, Xiangyang Gao, Shishang Guo*, Haiwu Zheng*, Yonghui Wu, Zhong Lin Wang*

DOI: 10.1002/EXP.20210152